The mighty Mississippi was the lifeblood of many Missouri towns for over a century. The Missouri Great River Road is a route with stories to tell and a history to preserve. Civil War History and the m... The Clarksville Museum, operated by a volunteer board, covers the history of the town from its founding in 1817
Clarksville, MO MuseumsThe Clarksville Tourist Information Center serves to showcase attractions and sights for those traveling the Great River Road. It overlooks the U. S. Lock and Dam #24, providing a close vantage point to view all river boat and barge traffic and a 'front row seat'
Clarksville, MO Visitors CentersThe mighty Mississippi was the lifeblood of many Missouri towns for over a century. The Missouri Great River Road is a route with stories to tell and a history to preserve. Civil War History and the movement west are just two of the great American stories that the byway has to tell.
Clarksville, MO Scenic BywaysThe commercial district in Clarksville is listed on the National Register of Historic Places
Clarksville, MO Historic DistrictsThe historic home of Champ Clark, speaker of the House of Representatives, 1911 - 1919. Restored with authentic and equivalen...
Mark Twain Boyhood Home and Museum, John Marshal Clemens Law Office, Grant's Drug Store, Pilaster House, Becky Thatcher's Hou...
Turn-of-the-century mansion, restored to its original splendor. Guided tours daily. Listed on the National Historic Regist...
Casino action with 500 slot machines and 16 table games including blackjack, roulette and craps....
RV sites, tent sites, electricity, trails....